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KMID : 0355220070320020201
Journal of Korean Academy Oral Medicine
2007 Volume.32 No. 2 p.201 ~ p.210
Application of Stress Hormones in Saliva in Research of Orofacial Pain Related with Stress
Ryu Ji-Won

Yoon Chang-Lyuk
Ahn Jong-Mo
Abstract
Many diseases occur by stress or effect of stress. The basis for using hormones in research of stress is the observation that most systems in the body show changes during stress and that hormonal markers in these changes are related with stress. Conceptually, the central role of sympathetic nervous system(SNS) and hypothalamus-pituitary-adrenal(HPA) axis activity in stress provides copious justification for measuring hormonal changes. Catecholamines like epinephrine and norepinephrine, cortisol, testosterone and growth hormone and so on show sensitive reaction to stress. The major advantage of salivary sample to stress research is that its sampling technique can be performed in non-stressful conditions and without physical restraint and ethical problems. Because hormone levels in saliva is a good reflection of hormone levels in plasma, application of stress hormones in saliva is very useful for research of orofacial pain related with stress.
KEYWORD
Stress, Hormone, Saliva, Orofacial pain
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